Studies on adsorption of diphtheria toxoid on aluminium phosphate gel
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چکیده
منابع مشابه
Removal of porphyrins from diphtheria toxoid by selective adsorption on Ecteola-cellulose.
The occurrence of porphyrins in diphtheria toxin is well known (for references, see A. M. Pappenheimer, J. Biol. Chem. 167:251, 1947). In toxoid, the porphyrins remain as red pigments which, unless removed before the addition of alum, impart a red color to the final alum-precipitated toxoid. Removal of the porphyrins as a first step was examined by L. B. Holt (Developments in Diphtheria Prophyl...
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T toxoid is one of the most successful vaccines used in immunization programme almost all over the world. Neonatal tetanus can be prevented by immunizing women of childbearing age with tetanus toxoid, either during pregnancy or outside of pregnancy. Tetanus vaccine is used either in mono or in combination with other antigens i.e. Diphtheria, Pertussis (whole cell or acellular), Hepatitis B, Hae...
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Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT. In the first step, following the purification of semi-crude DT by the ion-exchan...
متن کاملThe Purification and Concentration of Diphtheria Toxoid
By precipitation with acetone at 4 degrees C. a refined diphtheria toxoid was obtained as a dry powder, readily soluble in aqueous solutions. The powder itself appears to be stable. When dissolved in half the original volume of physiological salt solution, the toxoid remained stable, in the cold room, for a period of 7 months. Only toxoids should be used which have been completely detoxified by...
متن کاملPreparation and Evaluation of Diphtheria Toxoid-Containing Microspheres
Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT. In the first step, following the purification of semi-crude DT by the ion-exchan...
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ژورنال
عنوان ژورنال: Indian Journal of Science and Technology
سال: 2010
ISSN: 0974-6846,0974-5645
DOI: 10.17485/ijst/2010/v3i3.19